Grimes is a multidisciplinary artist who came to prominence with her album visions which she produced herself in GarageBand. This was followed by the critically acclaimed album Art Angels and the critically disliked (but much better-performing album) Miss Anthropocene, which were also both fully self-produced.

Some of her other artistic pursuits include scoring the Emmy-winning opening credits of the Netflix series Hilda and voicing a popstar cyborg in the video game Cyberpunk 2077. As a live act, she started out with many years of van touring but has worked her way up to a festival headliner.

Grimes is also a visual artist, often directing her music videos. She’s had one of the most successful NFT drops of all time and is known for her work in the digital art space. Her work with the AI music generation app Endel won the Apple Watch app of the year in 2020. A provocateur and philosopher, Grimes has been both criticized and lauded for her theories on AI, futurism, and luxury communism, among other topics.